Hossam El Beheiry

Research Synopsis

Currently, Dr. Beheiry’s extensive collaborative research is focused in the area of clinical neuroanethesia.  Studies are being conducted to develop new EEG indices for monitoring anesthetic depth.  Those studies showed that 4 to 12 Hz signal power was important in classifying states during maintenance of anesthesia and increasing the anesthetic depth promoted heightened phase coherence and strong cross-coupling between certain frequencies.  His group also demonstrated that propofol induction of anesthesia significantly reduced the amplitude of the 40-Hz auditory steady state response.  Furthermore, their supplementary research investigated blood conservation in major neurosurgical spine surgeries and neurological complications of regional anesthesia.       

Previously, novel experimental research has been performed to answer various questions pertaining to the mechanisms of postoperative cognitive dysfunction and strategies to improve anesthesia recovery profiles.  Dr. Beheiry’s group was able to elucidate important mechanisms of ageing potentiation of volatile anesthetic action that included the increased sensitivity of excitatory synaptic transmission in old animals.

Recent Publications

1. Haghigih SJJ, Hatzinakos D, El-Beheiry H (2015).  The effect of Propofol induced anaesthesia on Human 40-Hz Auditory Steady State Response.  Proceedings of the Canadian Conference on Electrical and Computer Engineering (CCECE), IEEE 28th, Halifax, NS, Canada, pages 812 – 817, 2015.
2. El Beheiry H, Mak P (2013). Effects of aging and propofol on the cardiovascular component of the autonomic nervous system.  J Clin Anesth 25(8):637-43.
3. El Beheiry H (2012).  Protecting the brain during neurosurgical procedures: strategies that can work.  Curr Opin Anaesthesiol 25(5):548-55.
4. Kang EE, Zalay OC, El Beheiry H, Wong J, del Campo M, Carlen PL, Bardakijan BL (2011).  Spectral features of electroencephalogram in characterizing various brain states under anesthesia.   Conf Proc IEEE Eng Med Biol Soc 2011:3099-102. 
5. Lupu CM, Kiehl TR, Chan VW, El-Beheiry H, Madden M, Brull R (2010).  Nerve expansion seen on ultrasound predicts histologic but not functional nerve injury after intraneural injection in pigs.  Reg Anesth Pain Med 35(2):132-9. 
6. Wong J, El Beheiry H, Rampersaud YR, Lewis S, Ahn H, De Silva Y, Abrishami A, Baig N, McBroom RJ, Chung F (2008).  Tranexamic Acid reduces perioperative blood loss in adult patients having spinal fusion surgery.  Anesth Analg 107(5):1479-86.
7. El Beheiry H, Ouanounou A, Carlen PL (2007).  L-type calcium channel blockade modifies anesthetic actions on aged hippocampal neurons. Neuroscience 147(1):117-26.

Appointments

Assistant Professor, Department of Anesthesia, University of Toronto
Staff Anesthetist, Department of Anesthesia, Trillium Health Partners

Honours and Awards

Name: Excellence in Medical Teaching
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Trillium Health Partners, 2014

Name: Postdoctoral Research Heart and Stroke Foundation Fellowship of Canada
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1995-1998

Name: Merck-Frost Fellowship for Clinical Pharmacology
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1990-1991

Name: UBC Graduate Fellowship, University of British Columbia
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1987-1989

Courses

Course Number: Clinical anesthesia
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Course Number: Airway skills on regional simulators
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