Haibo Zhang

Dr. Zhang’s translational research program focuses on the investigation of mechanisms and therapy in ARDS and sepsis from examining cell-cell interaction, molecular signaling, immune responses in cell models to testing ventilatory, pharmacological and cell delivery approaches in animal models and in clinical trials.  

Recent Publications

1. Fanelli V, Morita Y, Cappello P, Ghazarian M, Sugumar B, Delsedime L, Batt J, Ranieri VM, Zhang H, Slutsky AS. (2015). Neuromuscular blocking agent cisatracurium attenuates lung injury by inhibition of nicotinic acetylcholine receptor-a-1.  Critical Care Medicine. In press.
2. Zhang R, Pan Y, Fanelli V, Wu S, Luo AA, Islam D, Han B, Mao P, Ghazarian M, Zeng WM, Spieth P, Wang D, Khang J, Mo HY, Liu XQ, Uhlig S, Laffey J, Slutsky AS, Li Y, Zhang H.  (2015). Mechanical stress induces lung fibrosis via midkine signaling pathway. American Journal of Respiratory and Critical Care Medicine, 192 (3), 315-323.
3. Quinn KL, Henriques M, Tabuchi A, Han B, Yang H, Cheng WE, Tole S, Yu H, Luo A, Charbonney E, Tullis E, Lazarus A, Robinson LA, Ni H, Peterson BR, Kuebler WM, Slutsky AS, Zhang H. (2011).  Human neutrophil peptides mediate endothelial-monocyte interaction, foam cell formation, and platelet activation. Arteriosclerosis, Thrombosis and Vascular Biology, 31(9), 2070-2079.
4. Cabrera-Benitez NE, Laffey JG, Parotto M, Spieth PM, Villar J, Zhang H, Slutsky AS. (2014). Mechanical ventilation-associated lung fibrosis in acute respiratory distress syndrome: a significant contributor to poor outcome. Anesthesiology, 121(1), 189-198.
5. Voglis S, Quinn K, Tullis E, Liu M, Henriques M, Zubrinich C, Peñuelas O, Chan H, Silverman F, Cherepanov V, Orzech N, Khine AA, Cantin A, Slutsky AS, Downey GP, Zhang H. (2009). Human neutrophil peptides and phagocytic deficiency in bronchiectatic lungs. American Journal of Respiratory and Critical Care Medicine, 180(2), 159-166.

Appointments

Professor, Department of Medicine
Professor, Department of Physiology
Grant and Award Committee Member, Canadian Institutes of Health Research
Reappointment Committee Member, St. Michael’s Hospital
Animal Care Committee Member, St. Michael’s Hospital
Internal Peer Review Committee Chair, St. Michael’s Hospital
Appointment Committee Member, Institute of Medical Science, University of Toronto

Honours and Awards

Name: Premier Excellence Award
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Government of Ontario

Name: CIHR New Investigator Award
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Name: Chang Jiang Scholar
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Li Ka Shing Foundation

Courses

Course Number: Module on Preclinical Animal Models, Institute of Medical Sciences, University of Toronto, 1 hour, April 2, 2015
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